Identification of Novel Subcellular Localization and Trafficking of HIV-1 Nef Variants from Reference Strains G (F1.93.HH8793) and H (BE.93.VI997)
The human immunodeficiency virus type 1 (HIV-1) accessory protein Nef, plays an essential role in disease progression and pathogenesis via hijacking the host cellular CS-514 membrane-trafficking machinery.Interestingly, HIV-1 group-M subtypes display differences in the rate of disease progression.However, few reports investigated how the cellular b